your doctor may want to gradually reduce the dose oxycodone ap ap. if you have nausea, you may take this drug with food. common side effects include drowsiness, upset stomach, constipation and dry mouth oxycodone pregnancy. take 325 5 apap oxycodone exactly as directed by your doctor 40 mg oxycodone. the controlled-release product, oxycontin®, has a longer duration of action (8-12 hours). in addition, there are some people that should never take 325 5 apap oxycodone medications. this medication may cause dependence, especially if it has been used regularly for an extended period of time (more than a few weeks), or if it has been used in high doses. some of these long release preparations are also available in liquid form. always tell your doctor if you are currently taking medications for allergies, colds, motion sickness, sedatives or vitamins. oxycontin abusers often chew the tablets or crush the tablets and snort the powder. more severe side effects are less common, however, if you experience any of the following, you should contact your health care provider right away. if nausea persists or worsens, consult your doctor or pharmacist about alternatives for decreasing nausea (e difference between oxycodone and hydrocodone. if you wait until the pain has significantly worsened, the medication may not work as well. cimetidine (tagamet) increases the levels of 325 5 apap oxycodone in the blood and can thereby cause confusion, disorientation, seizures or respiratory depression. although the diversion and abuse of oxycontin® appeared initially in the eastern us, it has now spread to the western us including alaska and hawaii. most patients can tolerate this medication quite well oxycodone hydrocodone. as with most opiates, 325 5 apap oxycodone abuse may lead to dependence and tolerance oxycodone percocet. reports of pharmacies being broken in for 325 5 apap oxycodone are not uncommon. the main sources of 325 5 apap oxycodone on the street have been through forged prescriptions, professional diversion through unscrupulous pharmacists, doctors, and dentists, "doctor-shopping", and armed robberies and night break-ins of pharmacies and nursing homes. oxycontin is designed to be swallowed whole; however, abusers ingest the drug in a variety of ways. , cancer pain). this plus the relatively easy availability of the drug has made it liable to abuse. 325 5 apap oxycodone, [4,5-epoxy-14-hydroxy-3-methoxy-17-methyl-morphinan-6-one, dihydrohydroxycodeinone] is a semi-synthetic opioid agonist derived from thebaine, a constituent of opium. however, there are some side effects that are generally mild and for the most part, will not last a long time. swallow them whole. g. the manner of 325 5 apap oxycodone deaths cited included accidental (64%), suicide (19%), natural (15%) and undetermined (2%). pharmacological effects include analgesia, sedation, euphoria, feelings of relaxation, respiratory depression, constipation, papillary constriction, and cough suppression. according to the system to retrieve information from drug evidence, a federal database for drug seizures, 325 5 apap oxycodone seizures increased from 38 cases (51 drug exhibits) in 1998 to 221 cases (618 drug exhibits) in 2005 512 drug oxycodone. if you use this medication for an extended period of time, it may not be as effective and you will need a different dose. acetaminophen present in the combination products poses an additional risk of liver toxicity upon chronic abuse. acute overdose of 325 5 apap oxycodone can produce severe respiratory depression, skeletal muscle flaccidity, cold and clammy skin, reduction in blood pressure and heart rate, coma, respiratory arrest, and death. however, 325 5 apap oxycodone may cause addiction and withdrawal symptoms, difficulty breathing, as well as other harmful effects in a newborn baby when taken during pregnancy.